Dr. Chris Barnes

Lecturer in Systems Biology, Department of Cell and Environmental Biology, UCL

DepartmentOther
InterestsModelling mutational processes in the genome; Reverse engineering of signalling systems; Design of synthetic biological systems for therapeutic applications
Homepagehttps://www.ucl.ac.uk/cdb/research/barnes/
Emailchristopher.barnes (append @ucl.ac.uk)
Phone020 7679 7712

About Chris

I completed my PhD in experimental high energy physics at Imperial College / Fermilab in 2005. I worked for a short time at CERN and then moved to the Wellcome Trust Sanger Institute in 2006 to work in statistical genetics and Copy Number Variation (CNV). There I developed tools to perform robust association studies using CNV (called CNVtools). In 2009 I moved to the Theoretical Systems Biology Group at Imperial to work on inference in systems and synthetic biology models, Approximate Bayesian Computation (ABC) and stochastic modelling. In 2012 I moved to the Department of Cell and Developmental Biology at University College London to start my own research group in the area of computational systems and synthetic biology.

Research interests

The three main themes of my research all utilise mathematical modelling and statistical methods to gain insights into biological processes and their relation to disease.

  • Modelling mutational processes in the genome
  • Reverse engineering of signalling systems
  • Design of synthetic biological systems for therapeutic applications